David Main

Board Member

Focus at NTx

Leadership; Board Member


I am President and Chief Executive Officer of Notch Therapeutics. Previously, as Chairman and CEO of Aquinox Pharmaceuticals, a company I co-founded in 2006, I oversaw the advancement of the company’s lead product from target validation through Phase 3 clinical trials. I also led the transition of Aquinox from a private company to a NASDAQ-listed public company with approximately $300 million raised in equity capital and then completed the successful merger of Aquinox with Neoleukin Therapeutics.

Prior to my leadership of Aquinox, I served as President and CEO of INEX Pharmaceuticals and as a Vice President of QLT. I was formerly the Chair of LifeSciences BC (formerly BC Biotech), BIOTECanada and Accel-Rx, as well as a Director of BIO.org.

I began my career as a licensed pharmacist at the Royal Columbian Hospital in New Westminster, B.C. I hold a BSc (Pharmacy) and an MBA from the University of British Columbia (UBC).

Interests / hobbies

Golf, boating and cottage life.