NanoVation Co-founder and CEO Dr. Dominik (Dom) Witzigmann presented on the topic of “Advancing lipid nanoparticles for safe and efficient nucleic acid delivery to extrahepatic tissues” at CLINAM 2023 in Basel in October 2023.

Dr. Witzigmann discussed the revolutionary potential of LNP-enabled genetic medicines, and the pressing need to overcome the barrier of liver accumulation and limited extrahepatic biodistribution due to rapid clearance.

He highlighted NanoVation’s novel long-circulating LNP (lcLNP™) system as a response to this challenge, with its capacity to deliver nucleic acids to a variety of extrahepatic tissues due to its substantially enhanced blood circulation half-life.