Partnership

We develop innovative technologies that overcome the barriers to nucleic acid delivery as your catalytic partner in enabling your genetic medicines

We deliver

Whatever your delivery challenge, we can overcome it… together

With a comprehensive delivery toolbox at our disposal, we develop best-in-class LNP delivery technologies to meet your needs, whatever the payload or application.

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Karina Thorn wearing black rimmed glasses and a black blazer smiling nicely

Every genetic drug has a cargo and delivery component, which require dedicated innovation on both.

We look forward to partnering with NanoVation, as the company’s differentiated delivery platform could help Novo Nordisk to advance genetic medicine candidates with curative potential.

18 September 2024 press release

Karina Thorn, PhD

Corporate Vice President, Head of Research, Global Nucleic Acid Therapies, Novo Nordisk

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Salim Dhanji in the lab wearing a dark blazer and white dress shirt

Collaborating with NanoVationtx™ has been a transformative experience for ME Therapeutics. It has allowed us to rapidly enter the exciting field of therapeutic mRNA development.

NanoVation’s cutting-edge expertise in LNP delivery technology has swiftly advanced our efforts to target myeloid cells with precision. Their innovative lcLNP™ platform ensures efficient and targeted delivery—which is crucial for our cancer therapeutics.

Combining our immuno-oncology specialization with NanoVation’s leadership in RNA delivery technology opens exciting new avenues for effective treatments.

Salim Dhanji, PhD

CEO & Co-Founder, ME Therapeutics

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Josh in his lab

The need for mutation-proof vaccines was highlighted more than ever by the COVID pandemic. We at Baseimmune are tackling this problem by using AI to design next-generation antigens. We partnered with NanoVationtx™ to deliver these antigens using next-generation lipid nanoparticles, creating mRNA vaccines of the future.

Our company has high standards for the products and people we work with. Not only does NanoVationtx™ develop and deliver best-in-class technology, they share our vision to carry out the best science for the benefit of humankind.

Dr. Joshua Blight

CEO & Co-Founder, Baseimmune

|

Karina Thorn wearing black rimmed glasses and a black blazer smiling nicely

Every genetic drug has a cargo and delivery component, which require dedicated innovation on both.

We look forward to partnering with NanoVation, as the company’s differentiated delivery platform could help Novo Nordisk to advance genetic medicine candidates with curative potential.

18 September 2024 press release

Karina Thorn, PhD

Corporate Vice President, Head of Research, Global Nucleic Acid Therapies, Novo Nordisk

|

Salim Dhanji in the lab wearing a dark blazer and white dress shirt

Collaborating with NanoVationtx™ has been a transformative experience for ME Therapeutics. It has allowed us to rapidly enter the exciting field of therapeutic mRNA development.

NanoVation’s cutting-edge expertise in LNP delivery technology has swiftly advanced our efforts to target myeloid cells with precision. Their innovative lcLNP™ platform ensures efficient and targeted delivery—which is crucial for our cancer therapeutics.

Combining our immuno-oncology specialization with NanoVation’s leadership in RNA delivery technology opens exciting new avenues for effective treatments.

Salim Dhanji, PhD

CEO & Co-Founder, ME Therapeutics

|

Josh in his lab

The need for mutation-proof vaccines was highlighted more than ever by the COVID pandemic. We at Baseimmune are tackling this problem by using AI to design next-generation antigens. We partnered with NanoVationtx™ to deliver these antigens using next-generation lipid nanoparticles, creating mRNA vaccines of the future.

Our company has high standards for the products and people we work with. Not only does NanoVationtx™ develop and deliver best-in-class technology, they share our vision to carry out the best science for the benefit of humankind.

Dr. Joshua Blight

CEO & Co-Founder, Baseimmune

Our partnership approach

We’re in it with you, from start to finish

Planning

1

Collaborative workplan development

based on your target product profile (TPP):

  • Target tissue
  • Administration route
  • Nucleic payload
  • Therapeutic application

Collaborative workplan development

based on your target product profile (TPP):

  • Target tissue
  • Administration route
  • Nucleic payload
  • Therapeutic application

Customized lead development

2

Iterative design & development of LNPs

to identify and validate lead candidate with optimal efficacy & safety profile:

  • Selection & optimization of next-generation lipids
  • Design of RNA payload for improved activity at the target site
  • Rational LNP design to streamline candidate selection
  • Strategic pre-clinical proof-of-concept studies

Iterative design & development of LNPs

to identify and validate lead candidate with optimal efficacy & safety profile:

  • Selection & optimization of next-generation lipids
  • Design of RNA payload for improved activity at the target site
  • Rational LNP design to streamline candidate selection
  • Strategic pre-clinical proof-of-concept studies

Investigational new drug enablement

3

Seamless technology transfer

for downsteam scale-up & manufacturing:

  • Safety studies
  • Efficacy studies

Seamless technology transfer

for downsteam scale-up & manufacturing:

  • Safety studies
  • Efficacy studies

NanoVation Therapeutics™ can collaborate with you from end-to-end in the drug development process.

Once we’ve overcome your delivery challenge, we also offer you the option to license our toolbox.

Our pipeline

Durable gene expression for treating genetic diseases

Durable gene expression for treating genetic diseases

Adminstration route: i.v.

Platform technology: HepLNP

Modality: DNA

Indication: not disclosed

Strategy: partnership

Gene editing in extrahepatic tissues for treating genetic diseases

Gene editing in extrahepatic tissues for treating genetic diseases

Adminstration route: i.v.

Platform technology: lcLNP™

Modality: mRNA/gRNA

Indication: not disclosed

Strategy: partnership

Gene editing in hepatocytes for genetic disease

Gene editing in hepatocytes for genetic disease

Adminstration route: i.v.

Platform technology: HepLNP

Modality: mRNA/gRNA

Indication: not disclosed

Strategy: Partnered

Gene expression for cancer immunotherapy

Gene expression for cancer immunotherapy

Adminstration route: i.v.

Platform technology: lcLNP™

Modality: mRNA

Indication: not disclosed

Strategy: internal

Gene expression for healthy aging

Gene expression for healthy aging

Adminstration route: i.v.

Platform technology: combined

Modality: mRNA

Indication: not disclosed

Strategy: internal

Gene expression in tumors

Gene expression in tumors

Adminstration route: i.v.

Platform technology: lcLNP™

Modality: DNA

Indication: not disclosed

Strategy: partnership

Gene silencing in hepatocytes for genetic disease

Gene silencing in hepatocytes for genetic disease

Adminstration route: i.v.

Platform technology: HepLNP

Modality: siRNA

Indication: not disclosed

Strategy: partnership

Gene silencing in skin and adipose tissues for genetic disease

Gene silencing in skin and adipose tissues for genetic disease

Adminstration route: i.v.

Platform technology: lcLNP™

Modality: siRNA

Indication: not disclosed

Strategy: partnership

mRNA vaccine for viral diseases

mRNA vaccine for viral diseases

Adminstration route: i.m.

Platform technology: combined

Modality: mRNA

Indication: SARS & ASF

Strategy: partnership

No results found.

YOU

have a therapeutic application in mind

WE

develop the best-in-class delivery technology for you

YOU

have a therapeutic application in mind

WE

develop the best-in-class delivery technology for you

Finding solutions together

Let’s discuss how our proprietary platform technologies can help rapidly translate your nucleic acid therapeutic or vaccine into the clinic.